The Third Face of Vitamin C
维生素 C 的三种表现
Robert F. Cathcart, M.D.
罗伯特-F-卡斯卡特医学博士
Journal of Orthomolecular Medicine, 7:4;197-200, 1993.
《正分子医学杂志》(Journal of Orthomolecular Medicine),7:4;197-200,1993 年。
Copyright ©, 1994 and prior years by Dr. Robert F. Cathcart. Dr. Cathcart gave his permission “to distribute via the internet as long as material is distributed in its entirety and not modified.”
Robert F. Cathcart 博士版权所有 ©,1994 年及之前。卡斯卡特博士允许 “通过互联网传播,只要材料是完整的,未作修改”。
摘要
Bowel tolerance to orally ingested ascorbic acid increases with the toxicity of diseases. Bowel tolerance with a disease such as mononucleosis may reach 200 or more grams per 24 hours without it producing diarrhea. A marked clinical amelioration or cure is achieved in many disease processes when threshold doses near bowel tolerance are given. In a sense, it is the reducing equivalents carried by free radical scavengers that quench free radicals, not the free radical scavengers themselves. Ascorbic acid can be dramatically useful in quenching free radicals because it is usually tolerated in amounts necessary to provide the reducing equivalents necessary to quench almost all the free radicals generated by severe disease processes. Vitamin C functions are incidental at these dose levels; the benefit is from the reducing equivalents carried. To the extent that free radicals are either essential to the perpetuation of a disease or just part of the cause of symptoms, the disease will be cured or just ameliorated. These effects are even more dramatic from intravenous sodium ascorbate.
肠道对口服抗坏血酸的耐受性会随着疾病毒性的增加而增加。单核细胞增多症等疾病的肠道耐受性可达到每 24 小时 200 克或更多,而不会产生腹泻。在许多疾病的治疗过程中,如果服用的剂量接近肠道耐受量的临界值,就能明显改善临床症状或治愈疾病。从某种意义上说,淬灭自由基的是自由基清除剂所携带的还原等价物,而不是自由基清除剂本身。抗坏血酸在淬灭自由基方面的作用非常显著,因为它的耐受量通常足以提供淬灭严重疾病过程中产生的几乎所有自由基所需的还原当量。在这些剂量水平下,维生素 C 的功能是附带的;其益处来自于所携带的还原当量。如果自由基对疾病的持续存在至关重要,或者只是导致症状的部分原因,那么疾病就会被治愈,或者只是有所改善。静脉注射抗坏血酸钠的效果更为显著。
Keywords: vitamin C, ascorbate, acute induced scurvy, bowel tolerance, titrating to bowel tolerance, the ascorbate effect, free radical scavengers, reducing equivalents.
关键词:维生素 C、抗坏血酸盐、急性坏血病、肠道耐受性、滴定到肠道耐受性、抗坏血酸盐效应、自由基清除剂、还原当量。